PRF (platelet-rich fibrin) is an advanced form of PRP (platelet rich plasma) that is used to treat hair loss. It has been used for decades in dentistry and orthopedics. Human blood contains red blood cells, white blood cells, platelets, and plasma. When blood is centrifuged (or spun in a special way), it will produce PRF.
PRF contains platelets, white blood cells, fibrin and stem cells. Platelets in our blood contain proteins, or growth factors, that increase collagen production, regenerate tissue, tighten skin, rejuvenate texture of the skin, and improve hair regrowth. White blood cells aid in tissue regeneration, and fibrin acts as a scaffolding on which the growth factors attach to
allow a longer release of their growth factors. Stem cells are undifferentiated cells that can turn into specialized cells or become more stem cells. They act as a repair system for the body to replenish adult tissues.